Royal Air Force Typhoon FGR4s have operated alongside French aircraft in a coordinated attack against an hidden munitions depot in Syrian territory used by the IS group, according to the British defence ministry.
The location, located using surveillance, was assessed as containing munitions and bombs, the release indicated, and was situated in mountains just north of the historic site of Palmyra in Syria's central region.
"Our fighter planes used laser-guided Paveway IV weapons to strike a series of access tunnels providing entry to the depot... early reports indicate the strike was effective," the ministry announced.
There was no evidence of any harm to civilians in the strike late on Saturday and every plane involved returned to base without incident, the MoD added.
The Typhoon fighters were backed up by a Voyager refuelling tanker.
The Islamic State group - referred to as the so-called Islamic State - enforced extremist governance over parts of Iraq and Syria until 2019.
"This action demonstrates our UK leadership, and commitment to work closely with allied nations, to eradicate any revival of IS and their violent and radical beliefs in the Middle East," UK Defence Secretary the Defence Secretary said.
UK warplanes have conducted overwatch operations over Syria to "deter any attempted resurgence" of the group subsequent to its routing at the battle of Baghuz in 2019, the ministry said.
"I must thank the personnel of our armed forces who took part in this strike for their professionalism and their bravery," Healey commented. "They were among numerous British troops deployed over the festive period. This operation, to remove militants who endanger our safety, highlights how British military are prepared to act, all year round, keeping Britain secure domestically and strong abroad."
During December, the American forces carried out what it described as a "major assault" on Daesh sites in Syria, subsequent to an attack resulted in the deaths of two American soldiers and a civilian interpreter in Palmyra.
The United Nations says Islamic State still boasts an estimated 5,000 to 7,000 militants in both countries.
